Eisei Sohara Selected Research

Member 3 Solute Carrier Family 12

1/2019	Tacrolimus ameliorates the phenotypes of type 4 Bartter syndrome model mice through activation of sodium-potassium-2 chloride cotransporter and sodium-chloride cotransporter.
1/2018	Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats.
11/2015	Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.

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Eisei Sohara Research Topics

Disease

25	Pseudohypoaldosteronism 01/2022 - 10/2009
16	Chronic Renal Insufficiency 04/2024 - 03/2012
16	Hypertension (High Blood Pressure) 01/2022 - 10/2012
9	Hyperkalemia 04/2024 - 07/2005
6	Fibrosis (Cirrhosis) 10/2023 - 10/2017
6	Renal Insufficiency (Renal Failure) 01/2023 - 02/2017
5	Nephrogenic Diabetes Insipidus 01/2022 - 09/2006
5	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 10/2014
5	Hypokalemia 01/2022 - 10/2009
4	Proteinuria 01/2024 - 11/2013
4	Gitelman Syndrome 01/2022 - 01/2016
4	Bartter Syndrome (Syndrome, Bartter) 01/2021 - 11/2013
4	Alkalosis 01/2019 - 10/2009
3	Kidney Diseases (Kidney Disease) 04/2024 - 02/2017
3	Nephrotic Syndrome (Syndrome, Nephrotic) 04/2023 - 11/2013
3	Brain Diseases (Brain Disorder) 01/2022 - 01/2015
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 10/2012
3	Acute Kidney Injury (Acute Renal Failure) 11/2019 - 12/2005
3	Hypertrophy 01/2018 - 04/2005
2	COVID-19 01/2024 - 01/2023
2	Disease Progression 08/2023 - 01/2020
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2023 - 01/2021
2	Glomerulonephritis 01/2023 - 06/2013
2	Acidosis 01/2022 - 10/2014
2	Inflammation (Inflammations) 05/2021 - 01/2018
2	Polyuria 01/2021 - 01/2019
2	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2020 - 01/2019
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2020 - 03/2008
2	Renal hypouricemia 01/2020 - 11/2019
2	Hemorrhage 05/2018 - 01/2018
2	Sarcopenia 01/2018 - 01/2017
2	Diabetes Mellitus 01/2018 - 01/2018
2	Ischemia 08/2006 - 12/2005
1	Pulmonary Embolism 01/2024
1	Alzheimer Disease (Alzheimer's Disease) 10/2023
1	Hypesthesia (Numbness) 08/2023
1	Microscopic Polyangiitis 08/2023
1	Thrombotic Microangiopathies 08/2023
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 08/2023
1	Vasculitis (Vasculitides) 08/2023
1	Thrombocytopenia (Thrombopenia) 08/2023

Drug/Important Bio-Agent (IBA)

22	Phosphotransferases (Kinase)IBA 01/2022 - 10/2009
16	Lysine (L-Lysine)FDA Link 01/2022 - 10/2012
13	SaltsIBA 01/2021 - 08/2012
12	Proteins (Proteins, Gene)FDA Link 12/2022 - 08/2005
9	SodiumIBA 01/2022 - 10/2012
7	PotassiumIBA 04/2024 - 07/2005
6	ChloridesIBA 12/2022 - 12/2015
6	Proline (L-Proline)FDA Link 01/2020 - 10/2012
6	Alanine (L-Alanine)FDA Link 01/2020 - 10/2012
5	DiureticsIBA 01/2022 - 01/2016
4	CreatinineIBA 01/2023 - 11/2017
4	Cullin Proteins (Cullins)IBA 01/2020 - 10/2015
3	Adenine FDA LinkGeneric 10/2023 - 01/2018
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 12/2005
3	CalciumIBA 12/2022 - 01/2010
3	ElectrolytesIBA 01/2021 - 01/2016
3	Sodium Chloride SymportersIBA 01/2020 - 01/2018
3	Uric Acid (Urate)IBA 01/2020 - 11/2019
3	AntibodiesIBA 06/2019 - 11/2013
3	Member 3 Solute Carrier Family 12IBA 01/2019 - 11/2015
3	Vasopressins (Vasopressin)IBA 01/2019 - 11/2016
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 11/2015 - 09/2013
3	Glycerol (Glycerine)FDA LinkGeneric 08/2006 - 04/2005
2	Prednisolone (Predate)FDA LinkGeneric 01/2024 - 11/2013
2	Messenger RNA (mRNA)IBA 01/2023 - 01/2018
2	SymportersIBA 01/2022 - 05/2014
2	ReninIBA 01/2022 - 01/2019
2	ThiazidesIBA 01/2022 - 01/2016
2	CollagenIBA 11/2021 - 01/2018
2	LipidsIBA 05/2021 - 05/2018
2	Vitamin D FDA LinkGeneric 01/2021 - 06/2017
2	Serum AlbuminIBA 01/2021 - 02/2017
2	Tolvaptan FDA Link 01/2020 - 01/2019
2	Immunoglobulin G (IgG)IBA 06/2019 - 06/2017
2	Fibrinogen (Factor I)FDA Link 06/2019 - 06/2017
2	Factor XIII (Coagulation Factor XIII)IBA 06/2019 - 06/2017
2	Ligases (Synthetase)IBA 01/2018 - 01/2016
2	UbiquitinIBA 01/2018 - 01/2016
2	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2018 - 01/2017
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2015 - 03/2008
2	Cisplatin (Platino)FDA LinkGeneric 08/2006 - 12/2005
1	Dietary PotassiumIBA 04/2024
1	Fibronectins (Fibronectin)IBA 01/2024
1	ORALIT (ORS)IBA 01/2024
1	tau Proteins (tau Protein)IBA 10/2023
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 10/2023
1	Urea (Carbamide)FDA LinkGeneric 10/2023
1	Heparin (Liquaemin)FDA LinkGeneric 08/2023
1	avacopanIBA 08/2023
1	Anaphylatoxin C5a ReceptorIBA 08/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2023
1	intersectin 1IBA 04/2023
1	MicroRNAs (MicroRNA)IBA 01/2023
1	BNT162 VaccineIBA 01/2023

Therapy/Procedure

5	Renal Dialysis (Hemodialysis) 04/2024 - 01/2015
2	Protein-Restricted Diet (Diet, Protein Restricted) 01/2019 - 03/2012
2	Sodium-Restricted Diet (Diet, Sodium Restricted) 08/2011 - 10/2009
1	Renal Replacement Therapy (Therapies, Renal Replacement) 04/2024
1	Activities of Daily Living (ADL) 10/2023